Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays

This paper reported a feasibility study strategy of identifying pharmacokinetic (PK) markers for a cardiovascular herbal medicine, Guanxin Danshen drop pill (GDDP). First, quantification analysis revealed the constituent composition in the preparation by high-performance liquid chromatography (HPLC)...

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Опубликовано в: :Front Pharmacol
Главные авторы: Yao, Hong, Huang, Xiaomei, Xie, Yunjiao, Huang, Xuliang, Ruan, Yijun, Lin, Xinhua, Huang, Liying, Shi, Peiying
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308302/
https://ncbi.nlm.nih.gov/pubmed/30622470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01493
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