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miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition

Glioblastoma is the most aggressive and invasive brain tumor and has a poor prognosis; elucidating the underlying molecular mechanisms is essential to select molecular targeted therapies. Here, we investigated the effect of microRNAs on the marked invasiveness of glioblastoma. U373 glioblastoma cell...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Yachi, Kazuhiro, Tsuda, Masumi, Kohsaka, Shinji, Wang, Lei, Oda, Yoshitaka, Tanikawa, Satoshi, Ohba, Yusuke, Tanaka, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308238/
https://ncbi.nlm.nih.gov/pubmed/30603114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-018-0033-6
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