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Rejuvenation of β cells by epigenetic editing

Insulin-secreting β cell loss or dysfunction is a feature of both type 1 and type 2 diabetes. Strategies to restore β cell mass are limited, as sources of healthy islets are scarce and mature β cells are not readily expanded in vitro. In this issue of the JCI, Ou et al. report that mature β cell exp...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Wang, Tao, Pei, Duanqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307952/
https://ncbi.nlm.nih.gov/pubmed/30475229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124583
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