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Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation
Micronutrition is essential for neural tube closure, and zinc deficiency is associated with human neural tube defects. Here, we modeled zinc deficiency in mouse embryos, and used live imaging and molecular studies to determine how zinc deficiency affects neural tube closure. Embryos cultured with th...
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| Udgivet i: | Development |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6307889/ https://ncbi.nlm.nih.gov/pubmed/30545932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.169797 |
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