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The variant at TGFBRAP1 is significantly associated with type 2 diabetes mellitus and affects diabetes‐related miRNA expression

While the transforming growth factor‐β1 (TGF‐β1) regulates the growth and proliferation of pancreatic β‐cells, its receptors trigger the activation of Smad network and subsequently induce the insulin resistance. A case‐control was conducted to evaluate the associations of the polymorphisms of TGF‐β1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Yang, Song, Chen, Xiaotian, Yang, Mengyao, Zhao, Xianghai, Chen, Yanchun, Zhao, Hailong, Liu, Chunlan, Shen, Chong
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307842/
https://ncbi.nlm.nih.gov/pubmed/30461200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13885
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