Cardiac‐specific Mst1 deficiency inhibits ROS‐mediated JNK signalling to alleviate Ang II‐induced cardiomyocyte apoptosis

Apoptosis is associated with various myocardial diseases. Angiotensin II (Ang II) plays a central role in the pathogenesis of RAAS‐triggered cardiac apoptosis. Our previous studies showed that mammalian Ste20‐like kinase 1 (Mst1) aggravates cardiac dysfunction in cardiomyocyte under pathological con...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Cheng, Zheng, Zhang, Mingming, Hu, Jianqiang, Lin, Jie, Feng, Xinyu, Wang, Shanjie, Wang, Tingting, Gao, Erhe, Wang, Haichang, Sun, Dongdong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307828/
https://ncbi.nlm.nih.gov/pubmed/30338935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13958
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