Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation

Key regulators of the Wnt signalling, DVL1, DVL2 and DVL3, in astrocytomas of different malignancy grades were investigated. Markers for DVL1,DVL2 and DVL3 were used to detect microsatellite instability (MSI) and gross deletions (LOH), while immunohistochemistry and immunoreactivity score were used...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Kafka, Anja, Bačić, Mateja, Tomas, Davor, Žarković, Kamelija, Bukovac, Anja, Njirić, Niko, Mrak, Goran, Krsnik, Željka, Pećina‐Šlaus, Nives
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307814/
https://ncbi.nlm.nih.gov/pubmed/30468298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13969
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