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Deciphering molecular properties of hypermutated gastrointestinal cancer

Great mutational heterogeneity is observed both across cancer types (>1000‐fold) and within a given cancer type, with a fraction harboring >10 mutations per million bases, thus termed hypermutation. We determined the genome‐wide effects of high mutation load on the transcriptome and methylome...

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Bibliografiska uppgifter
I publikationen:J Cell Mol Med
Huvudupphovsmän: Hu, Wangxiong, Yang, Yanmei, Ge, Weiting, Zheng, Shu
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307802/
https://ncbi.nlm.nih.gov/pubmed/30381870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13941
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