Liraglutide protects against glucolipotoxicity‐induced RIN‐m5F β‐cell apoptosis through restoration of PDX1 expression

Prolonged exposure to high levels of glucose and fatty acid (FFA) can induce tissue damage commonly referred to as glucolipotoxicity and is particularly harmful to pancreatic β‐cells. Glucolipotoxicity‐mediated β‐cell failure is a critical causal factor in the late stages of diabetes, which suggests...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Kornelius, Edy, Li, Hsin‐Hua, Peng, Chiung‐Huei, Yang, Yi‐Sun, Chen, Wei‐Jen, Chang, Yan‐Zin, Bai, Yi‐Chiao, Liu, Stanley, Huang, Chien‐Ning, Lin, Chih‐Li
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307795/
https://ncbi.nlm.nih.gov/pubmed/30353648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13967
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