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HIF-α/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells

The present study investigated the mechanism underlying the protective effect of dexmedetomidine (Dex) on hippocampal neuronal HT22 cell apoptosis induced by the anesthetics isoflurane and bupivacaine. The cellular morphology was observed using a phase contrast microscope. The effects of anesthetics...

詳細記述

保存先:
書誌詳細
出版年:Exp Ther Med
主要な著者: Bao, Fangping, Kang, Xianhui, Xie, Qing, Wu, Jian
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307527/
https://ncbi.nlm.nih.gov/pubmed/30651766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6956
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