Polymorphisms in Manganese Transporters SLC30A10 and SLC39A8 Are Associated With Children's Neurodevelopment by Influencing Manganese Homeostasis

Background: Manganese (Mn) is an essential element but at excessive levels, it is neurotoxic. Even a moderate increase in Mn has been suggested to interfere with neurodevelopment in children. Genetics influencing Mn concentrations and toxicity is unclear. Objective: We assessed, in a cross-sectional...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wahlberg, Karin E., Guazzetti, Stefano, Pineda, Daniela, Larsson, Susanna C., Fedrighi, Chiara, Cagna, Giuseppa, Zoni, Silvia, Placidi, Donatella, Wright, Robert O., Smith, Donald R., Lucchini, Roberto G., Broberg, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307466/
https://ncbi.nlm.nih.gov/pubmed/30619481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00664
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