IL-6 Impairs Vaccine Responses in Neonatal Mice

The inability of infants to mount proper follicular helper T (T(FH)) cell response renders this age group susceptible to infectious diseases. Initial instruction of T cells by antigen presenting cells and subsequent differentiation into T(FH) cells are controlled by T cell receptor signal strength,...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Yang, Jiyeon, Sakai, Jiro, Siddiqui, Shafiuddin, Lee, Robert C., Ireland, Derek D. C., Verthelyi, Daniela, Akkoyunlu, Mustafa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307459/
https://ncbi.nlm.nih.gov/pubmed/30619375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03049
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