Obinutuzumab pretreatment abrogates tumor lysis risk while maintaining undetectable MRD for venetoclax + obinutuzumab in CLL

Early data on venetoclax-containing regimens for the treatment of chronic lymphocytic leukemia (CLL) show promising results with deep remissions, but are hampered by potential risk for tumor lysis syndrome (TLS). Whether optimal duration of venetoclax treatment can be guided by minimal residual dise...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Kater, Arnon P., Kersting, Sabina, van Norden, Yvette, Dubois, Julie, Dobber, Johan A., Mellink, Clemens H., Evers, Ludo M., Croon-de Boer, Fransien, Schreurs, John, van der Spek, Ellen, Visser, Hein, Idink, Cecile, Wittebol, Shulamiet, Hoogendoorn, Mels, Tonino, Sanne H., Mobasher, Mehrdad, Levin, Mark-David
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306887/
https://ncbi.nlm.nih.gov/pubmed/30552161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019422
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