An EGFR-mutated Lung Adenocarcinoma Undergoing Squamous Cell Carcinoma Transformation Exhibited a Durable Response to Afatinib

Squamous cell carcinoma (SCC) transformation has been identified as a mechanism of resistance to first-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), gefitinib or erlotinib, in EGFR-mutated lung cancer. However, whether second- or third-generation TKIs can overco...

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Vydáno v:Intern Med
Hlavní autoři: Sato, Mitsuo, Matsui, Akira, Shimoyama, Yoshie, Omote, Norihito, Morise, Masahiro, Hase, Tetsunari, Tanaka, Ichidai, Suzuki, Kojiro, Hasegawa, Yoshinori
Médium: Artigo
Jazyk:Inglês
Vydáno: The Japanese Society of Internal Medicine 2018
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306534/
https://ncbi.nlm.nih.gov/pubmed/30101911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.0999-18
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