TRH Analog, Taltirelin Protects Dopaminergic Neurons From Neurotoxicity of MPTP and Rotenone

Dopaminergic neurons loss is one of the main pathological characters of Parkinson’s disease (PD), while no suitable neuroprotective agents have been in clinical use. Thyrotropin-releasing hormone (TRH) and its analogs protect neurons from ischemia and various cytotoxins, but whether the effect also...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Zheng, Cong, Chen, Guiqin, Tan, Yang, Zeng, Weiqi, Peng, Qiwei, Wang, Ji, Cheng, Chi, Yang, Xiaoman, Nie, Shuke, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Ye, Keqiang, Cao, Xuebing
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306470/
https://ncbi.nlm.nih.gov/pubmed/30618632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00485
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