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Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca(2+) Signaling and Mitochondrial Function in the Exocrine Pancreas

Cystic fibrosis (CF) is the most common genetic disorder that causes a significant damage in secretory epithelial cells due to the defective ion flux across the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel. Pancreas is one of the organs most frequently damaged by the dise...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Madácsy, Tamara, Pallagi, Petra, Maleth, Jozsef
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306458/
https://ncbi.nlm.nih.gov/pubmed/30618777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01585
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