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miRNA arm switching identifies novel tumour biomarkers

BACKGROUND: microRNAs have been reported to play critical roles in cancer and to have potential as diagnostic biomarkers. During miRNA biogenesis, one strand of the miRNA hairpin precursor is preferentially selected as a functionally mature miRNA, while the other strand is typically degraded. Arm sw...

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Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Chen, Liang, Sun, Huiyan, Wang, Changliang, Yang, Yang, Zhang, Menglei, Wong, Garry
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306400/
https://ncbi.nlm.nih.gov/pubmed/30425004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.003
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