miRNA arm switching identifies novel tumour biomarkers

BACKGROUND: microRNAs have been reported to play critical roles in cancer and to have potential as diagnostic biomarkers. During miRNA biogenesis, one strand of the miRNA hairpin precursor is preferentially selected as a functionally mature miRNA, while the other strand is typically degraded. Arm sw...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Chen, Liang, Sun, Huiyan, Wang, Changliang, Yang, Yang, Zhang, Menglei, Wong, Garry
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306400/
https://ncbi.nlm.nih.gov/pubmed/30425004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.003
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