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Altered Expression of Mitochondrial NAD(+) Carriers Influences Yeast Chronological Lifespan by Modulating Cytosolic and Mitochondrial Metabolism
Nicotinamide adenine dinucleotide (NAD(+)) represents an essential cofactor in sustaining cellular bioenergetics and maintaining cellular fitness, and has emerged as a therapeutic target to counteract aging and age-related diseases. Besides NAD(+) involvement in multiple redox reactions, it is also...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6305841/ https://ncbi.nlm.nih.gov/pubmed/30619489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00676 |
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