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Design and Development of Modified mRNA Encoding Core Antigen of Hepatitis C Virus: a Possible Application in Vaccine Production

BACKGROUND: Hepatitis C virus (HCV) is a blood-borne pathogen, resulting in liver cirrhosis and liver cancer. Despite of many efforts in development of treatments for HCV, no vaccine has been licensed yet. The purpose of this study was to design and prepare a specific mRNA, without 5’ cap and poly (...

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Bibliografische gegevens
Gepubliceerd in:Iran Biomed J
Hoofdauteurs: Sharifnia, Zarin, Bandehpour, Mojgan, Kazemi, Bahram, Zarghami, Nosratollah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Pasteur Institute 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305823/
https://ncbi.nlm.nih.gov/pubmed/30056690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/.23.1.57
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