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UPR Induction Prevents Iron Accumulation and Oligodendrocyte Loss in ex vivo Cultured Hippocampal Slices

The accumulation of iron within the brain occurs in many chronic disorders including Alzheimer’s and Parkinson’s disease and multiple sclerosis. Outside the CNS, a link between levels of iron and the unfolded protein response has already been established. To determine if such a relationship operates...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Healy, Sinead, McMahon, Jill, FitzGerald, Una
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305600/
https://ncbi.nlm.nih.gov/pubmed/30618588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00969
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