Effect of Genotype and Maternal Affective Disorder on Intronic Methylation of FK506 Binding Protein 5 in Cord Blood DNA

A single nucleotide polymorphism (SNP: rs1360780) in FKBP5 (FK506 Binding Protein 5) has been shown to interact with exposure to childhood adversity to promote loss of methylation and increase in gene expression in adults. We asked whether rs1360780 can influence FKBP5 intronic methylation in the co...

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Vydáno v:Front Genet
Hlavní autoři: Duis, Jessica, Cox, Olivia H., Ji, Yuelong, Seifuddin, Fayaz, Lee, Richard S., Wang, Xiaobin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305129/
https://ncbi.nlm.nih.gov/pubmed/30619472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00648
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