The Therapeutic Effect of STAT3 Signaling-Suppressed MSC on Pain and Articular Cartilage Damage in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis

Osteoarthritis (OA) is a degenerative disease that induces pain, cartilage deformation, and joint inflammation. Mesenchymal stem cells (MSCs) are potential therapeutic agents for treatment of OA. However, MSC therapy can cause excessive inflammation. Signal transducer and activator of transcription...

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Опубликовано в: :Front Immunol
Главные авторы: Lee, Seon-yeong, Lee, Seung Hoon, Na, Hyun Sik, Kwon, Ji Ye, Kim, Goo-Young, Jung, KyungAh, Cho, Keun-Hyung, Kim, Seon Ae, Go, Eun Jeong, Park, Min-Jung, Baek, Jin-Ah, Choi, Si Young, Jhun, JooYeon, Park, Sung-Hwan, Kim, Seok Jung, Cho, Mi-La
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305125/
https://ncbi.nlm.nih.gov/pubmed/30619261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02881
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