The Therapeutic Effect of STAT3 Signaling-Suppressed MSC on Pain and Articular Cartilage Damage in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis

Osteoarthritis (OA) is a degenerative disease that induces pain, cartilage deformation, and joint inflammation. Mesenchymal stem cells (MSCs) are potential therapeutic agents for treatment of OA. However, MSC therapy can cause excessive inflammation. Signal transducer and activator of transcription...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Lee, Seon-yeong, Lee, Seung Hoon, Na, Hyun Sik, Kwon, Ji Ye, Kim, Goo-Young, Jung, KyungAh, Cho, Keun-Hyung, Kim, Seon Ae, Go, Eun Jeong, Park, Min-Jung, Baek, Jin-Ah, Choi, Si Young, Jhun, JooYeon, Park, Sung-Hwan, Kim, Seok Jung, Cho, Mi-La
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305125/
https://ncbi.nlm.nih.gov/pubmed/30619261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02881
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