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Structure and activity of lipid bilayer within a membrane-protein transporter

Membrane proteins function in native cell membranes, but extraction into isolated particles is needed for many biochemical and structural analyses. Commonly used detergent-extraction methods destroy naturally associated lipid bilayers. Here, we devised a detergent-free method for preparing cell-memb...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qiu, Weihua, Fu, Ziao, Xu, Guoyan G., Grassucci, Robert A., Zhang, Yan, Frank, Joachim, Hendrickson, Wayne A., Guo, Youzhong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304963/
https://ncbi.nlm.nih.gov/pubmed/30509977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812526115
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