Dexmedetomidine Ameliorates the Neurotoxicity of Sevoflurane on the Immature Brain Through the BMP/SMAD Signaling Pathway

Numerous studies have demonstrated that general anesthetics might damage the nervous system, thus, the effect of general anesthetics on the developing brain has attracted much attention. Dexmedetomidine (Dex) exhibits a certain neuroprotective effect, but the mechanism is obscure. In our study, preg...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Shan, Yangyang, Yang, Fan, Tang, Zhiyin, Bi, Congjie, Sun, Shiwei, Zhang, Yongfang, Liu, Hongtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304752/
https://ncbi.nlm.nih.gov/pubmed/30618586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00964
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