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Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages
BACKGROUND AND PURPOSE: Cigarette smoke (CS) induces alveolar destruction through overproduction of proteinases including matrix metalloproteinase (MMP)-9 by alveolar macrophages (AMs). Receptor activator of nuclear factor-κB ligand (RANKL) functions in immune regulation and cytokine secretion; whet...
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| Veröffentlicht in: | Int J Chron Obstruct Pulmon Dis |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6304243/ https://ncbi.nlm.nih.gov/pubmed/30587964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S190023 |
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