Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a uniformly fatal CNS tumor diagnosed in 300 American children per year. Radiation is the only effective treatment and extends overall survival to a median of 11 months. Due to its location in the brainstem, DIPG cannot be surgically resected. I...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lieberman, Nicole A P, DeGolier, Kole, Kovar, Heather M, Davis, Amira, Hoglund, Virginia, Stevens, Jeffrey, Winter, Conrad, Deutsch, Gail, Furlan, Scott N, Vitanza, Nicholas A, Leary, Sarah E S, Crane, Courtney A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303470/
https://ncbi.nlm.nih.gov/pubmed/30169876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy145
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