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The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells

The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. However, the lack of a functionally null mutant has ha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Geng, Ruishuang, Furness, David N, Muraleedharan, Chithra K, Zhang, Jinsheng, Dabdoub, Alain, Lin, Vincent, Xu, Shunbin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303392/
https://ncbi.nlm.nih.gov/pubmed/30575790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36894-z
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