Haplotypes in the CYP2R1 gene are associated with levels of 25(OH)D and bone mineral density, but not with other markers of bone metabolism (MrOS Sweden)

OBJECTIVE: Polymorphisms in the CYP2R1 gene encoding Vitamin D 25-hydroxylase have been reported to correlate with circulating levels of 25-OH vitamin D3 (25(OH)D). It is unknown whether these variations also affect overall bone metabolism. In order to elucidate the overall associations of polymorph...

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Veröffentlicht in:PLoS One
Hauptverfasser: Björk, Anne, Mellström, Dan, Ohlsson, Claes, Karlsson, Magnus, Mallmin, Hans, Johansson, Gunnar, Ljunggren, Östen, Kindmark, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303094/
https://ncbi.nlm.nih.gov/pubmed/30576350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209268
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