Different duration of parathyroid hormone exposure distinctively regulates primary response genes Nurr1 and RANKL in osteoblasts

Parathyroid hormone (PTH) exerts dual effects, anabolic or catabolic, on bone when administrated intermittently or continuously, via mechanisms that remain largely unknown. PTH binding to cells induces PTH-responsive genes including primary response genes (PRGs). PRGs are rapidly induced without the...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Choi, Hyewon, Magyar, Clara E., Nervina, Jeanne M., Tetradis, Sotirios
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303058/
https://ncbi.nlm.nih.gov/pubmed/30576321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208514
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