Effects of RNA structure and salt concentration on the affinity and kinetics of interactions between pentatricopeptide repeat proteins and their RNA ligands

Pentatricopeptide repeat (PPR) proteins are helical repeat proteins that bind specific RNA sequences via modular 1-repeat:1-nucleotide interactions. Binding specificity is dictated, in part, by hydrogen bonds between the amino acids at two positions in each PPR motif and the Watson-Crick face of the...

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Bibliographic Details
Published in:PLoS One
Main Authors: McDermott, James J., Civic, Bryce, Barkan, Alice
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303017/
https://ncbi.nlm.nih.gov/pubmed/30576379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209713
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