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Effects of RNA structure and salt concentration on the affinity and kinetics of interactions between pentatricopeptide repeat proteins and their RNA ligands

Pentatricopeptide repeat (PPR) proteins are helical repeat proteins that bind specific RNA sequences via modular 1-repeat:1-nucleotide interactions. Binding specificity is dictated, in part, by hydrogen bonds between the amino acids at two positions in each PPR motif and the Watson-Crick face of the...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: McDermott, James J., Civic, Bryce, Barkan, Alice
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303017/
https://ncbi.nlm.nih.gov/pubmed/30576379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209713
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