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Delivery of genome editing tools by bacterial extracellular vesicles

Here we propose to use bacterial cells as factories that generate EVs harboring both the RNP complex (or any other CRISPR‐mediated tool) and a specific ligand molecule. The ligand would allow specific binding of EVs to cells with the matching receptors, adding a level of specificity to the delivery,...

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Bibliografische gegevens
Gepubliceerd in:Microb Biotechnol
Hoofdauteurs: Liu, Yue, Smid, Eddy J., Abee, Tjakko, Notebaart, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302703/
https://ncbi.nlm.nih.gov/pubmed/30549228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.13356
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