Transcriptomic and fluxomic changes in Streptomyces lividans producing heterologous protein

BACKGROUND: The Gram-positive Streptomyces lividans TK24 is an attractive host for heterologous protein production because of its high capability to secrete proteins—which favors correct folding and facilitates downstream processing—as well as its acceptance of methylated DNA and its low endogeneous...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Daniels, Wouter, Bouvin, Jeroen, Busche, Tobias, Rückert, Christian, Simoens, Kenneth, Karamanou, Spyridoula, Van Mellaert, Lieve, Friðjónsson, Ólafur H., Nicolai, Bart, Economou, Anastassios, Kalinowski, Jörn, Anné, Jozef, Bernaerts, Kristel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302529/
https://ncbi.nlm.nih.gov/pubmed/30577858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1040-6
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