Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone

Bone mass is maintained by a balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Although recent genetic studies have uncovered various mechanisms that regulate osteoblast differentiation, the molecular basis of osteoblast proliferation remains unclear. Here,...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Takahashi, Akira, Mulati, Mieradili, Saito, Masanori, Numata, Hoashi, Kobayashi, Yutaka, Ochi, Hiroki, Sato, Shingo, Kaldis, Philipp, Okawa, Atsushi, Inose, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302182/
https://ncbi.nlm.nih.gov/pubmed/30366983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004834
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