Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites

Different transcription factors operate together at promoters and enhancers to regulate gene expression. Transcription factors either bind directly to their target DNA or are tethered to it by other proteins. The transcription factor Sp2 serves as a paradigm for indirect genomic binding. It does not...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Völkel, Sara, Stielow, Bastian, Finkernagel, Florian, Berger, Dana, Stiewe, Thorsten, Nist, Andrea, Suske, Guntram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302174/
https://ncbi.nlm.nih.gov/pubmed/30337366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005341
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