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Direct interactions between the secreted effector and the T2SS components GspL and GspM reveal a new effector-sensing step during type 2 secretion

In many Gram-negative bacteria, the type 2 secretion system (T2SS) plays an important role in virulence because of its capacity to deliver a large amount of fully folded protein effectors to the extracellular milieu. Despite our knowledge of most T2SS components, the mechanisms underlying effector r...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Michel-Souzy, Sandra, Douzi, Badreddine, Cadoret, Frédéric, Raynaud, Claire, Quinton, Loïc, Ball, Geneviève, Voulhoux, Romé
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302157/
https://ncbi.nlm.nih.gov/pubmed/30337370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001127
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