Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

Background: The role of GABA-B neurotransmission in addiction has recently received increased attention, with clinical trials indicating that baclofen, a GABA-B receptor agonist, may reduce alcohol consumption, craving and promote abstinence. However, the optimal dose to treat alcohol dependence is...

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Bibliografske podrobnosti
izdano v:Front Psychiatry
Main Authors: Durant, Claire F., Paterson, Louise M., Turton, Sam, Wilson, Susan J., Myers, James F. M., Muthukumaraswamy, Suresh, Venkataraman, Ashwin, Mick, Inge, Paterson, Susan, Jones, Tessa, Nahar, Limon K., Cordero, Rosa E., Nutt, David J., Lingford-Hughes, Anne
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Psychiatry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302106/
https://ncbi.nlm.nih.gov/pubmed/30618857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00664
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