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Mathematical-model-guided development of full-thickness epidermal equivalent

Epidermal equivalents prepared with passaged keratinocytes are typically 10–20 μm thick, whereas intact human epidermis is up to 100 μm thick. Our established mathematical model of epidermal homeostasis predicted that the undulatory pattern of the papillary layer beneath the epidermis is a key deter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumamoto, Junichi, Nakanishi, Shinobu, Makita, Mio, Uesaka, Masaaki, Yasugahira, Yusuke, Kobayashi, Yasuaki, Nagayama, Masaharu, Denda, Sumiko, Denda, Mitsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301960/
https://ncbi.nlm.nih.gov/pubmed/30573749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36647-y
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