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RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation

In Drosophila melanogaster, the male-specific lethal (MSL) complex plays a key role in dosage compensation by stimulating expression of male X-chromosome genes. It consists of MSL proteins and two long noncoding RNAs, roX1 and roX2, that are required for spreading of the complex on the chromosome an...

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Vydáno v:PLoS Genet
Hlavní autoři: Kim, Maria, Faucillion, Marie-Line, Larsson, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301720/
https://ncbi.nlm.nih.gov/pubmed/30532158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007842
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