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Deciphering the ATP-binding mechanism(s) in NLRP-NACHT 3D models using structural bioinformatics approaches

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), the first line of defense, are the cytosolic pattern recognition receptors (PRRs) that regulate the inflammatory activity in response to invading pathogens. NLRs are the members of AAA+ ATPase superfamily that comprises of N-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Maharana, Jitendra, Panda, Debashis, De, Sachinandan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301626/
https://ncbi.nlm.nih.gov/pubmed/30571723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209420
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