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Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1H)-one-3-carboxamide scaffold

Cannabinoid type 2 (CB(2)) receptor has been implicated in several diseases and conditions, however no CB(2) receptor selective drugs have made it to market. The aim of this study was to develop fluorescent ligands as CB(2) receptor tools, to enable an increased understanding of CB(2) receptor expre...

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Bibliografiske detaljer
Udgivet i:Medchemcomm
Main Authors: Cooper, Anna G., Oyagawa, Caitlin R. M., Manning, Jamie J., Singh, Sameek, Hook, Sarah, Grimsey, Natasha L., Glass, Michelle, Tyndall, Joel D. A., Vernall, Andrea J.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301273/
https://ncbi.nlm.nih.gov/pubmed/30647881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00448j
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