MGMT is down-regulated independently of promoter DNA methylation in rats with all-trans retinoic acid-induced spina bifida aperta

O6-methylguanine DNA methyltransferase (MGMT), a DNA repair enzyme, has been reported in some congenital malformations, but it is less frequently reported in neural tube defects. This study investigated MGMT mRNA expression and methylation levels in the early embryo and in different embryonic stages...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neural Regen Res
Egile Nagusiak: Zhang, He-Nan, Guo, Yi, Ma, Wei, Xue, Jia, Wang, Wei-Lin, Yuan, Zheng-Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Medknow Publications & Media Pvt Ltd 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301176/
https://ncbi.nlm.nih.gov/pubmed/30531021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.244799
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