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Inflammation and Monocyte Recruitment Due to Aging and Mechanical Stretch in Alveolar Epithelium are Inhibited by the Molecular Chaperone 4-Phenylbutyrate

INTRODUCTION: Ventilator-Induced lung injury (VILI) is a form of acute lung injury that is initiated or exacerbated by mechanical ventilation. The aging lung is also more susceptible to injury. Harmful mechanical stretch of the alveolar epithelium is a recognized mechanism of VILI, yet little is kno...

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Détails bibliographiques
Publié dans:Cell Mol Bioeng
Auteurs principaux: Valentine, M. S., Link, P. A., Herbert, J. A., Kamga Gninzeko, F. J., Schneck, M. B., Shankar, K., Nkwocha, J., Reynolds, A. M., Heise, R. L.
Format: Artigo
Langue:Inglês
Publié: Springer US 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301058/
https://ncbi.nlm.nih.gov/pubmed/30581495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-018-0537-8
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