Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis

Gomisin C (GC) and gomisin G (GG) are two lignan analogs isolated from the Traditional Chinese Medicine Schisandra chinensis which possesses multiple pharmacological activities. However, the potential herb-drug interactions (HDI) between these lignans and other drugs through inhibiting human cytochr...

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Publicat a:Fitoterapia
Autors principals: Zhao, Jin, Sun, Tao, Jing-Jing, Wu, Yun-Feng, Cao, Zhong-Ze, Fang, Hong-Zhi, Sun, Zhi-Tu, Zhu, Yang, Kun, Yong-Zhe, Liu, Gonzalez, Frank J., Yin, Jun
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300986/
https://ncbi.nlm.nih.gov/pubmed/28344076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fitote.2017.03.010
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