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Detection of Innate and Artificial Mitochondrial DNA Heteroplasmy by Massively Parallel Sequencing: Considerations for Analysis

BACKGROUND: Mitochondrial heteroplasmy, the co-existence of different mitochondrial polymorphisms within an individual, has various forensic and clinical implications. But there is still no guideline on the application of massively parallel sequencing (MPS) in heteroplasmy detection. We present here...

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Pubblicato in:J Korean Med Sci
Autori principali: Kim, Moon-Young, Cho, Sohee, Lee, Ji Hyun, Seo, Hee Jin, Lee, Soong Deok
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Academy of Medical Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300661/
https://ncbi.nlm.nih.gov/pubmed/30584415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2018.33.e337
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