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Detection of Innate and Artificial Mitochondrial DNA Heteroplasmy by Massively Parallel Sequencing: Considerations for Analysis

BACKGROUND: Mitochondrial heteroplasmy, the co-existence of different mitochondrial polymorphisms within an individual, has various forensic and clinical implications. But there is still no guideline on the application of massively parallel sequencing (MPS) in heteroplasmy detection. We present here...

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Detalhes bibliográficos
Publicado no:J Korean Med Sci
Main Authors: Kim, Moon-Young, Cho, Sohee, Lee, Ji Hyun, Seo, Hee Jin, Lee, Soong Deok
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300661/
https://ncbi.nlm.nih.gov/pubmed/30584415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2018.33.e337
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