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The potential role for infections in the pathogenesis of autoimmune Addison’s disease

Autoimmune Addison’s disease (AAD), or primary adrenocortical insufficiency, is a classical organ‐specific autoimmune disease with 160 years of history. AAD is remarkably homogeneous with one major dominant self‐antigen, the cytochrome P450 21‐hydroxylase enzyme, which is targeted by both autoantibo...

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Bibliographic Details
Published in:Clin Exp Immunol
Main Authors: Hellesen, A., Bratland, E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300649/
https://ncbi.nlm.nih.gov/pubmed/30144040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13207
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