Probiotic Exopolysaccharide Protects against Systemic Staphylococcus aureus Infection, Inducing Dual-Functioning Macrophages That Restrict Bacterial Growth and Limit Inflammation

Staphylococcus aureus causes severe systemic infection with high mortality rates. We previously identified exopolysaccharide (EPS) from a probiotic, Bacillus subtilis, that induces anti-inflammatory macrophages with an M2 phenotype and protects mice from Citrobacter rodentium-induced colitis. We tes...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Paik, Wonbeom, Alonzo, Francis, Knight, Katherine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300633/
https://ncbi.nlm.nih.gov/pubmed/30396894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00791-18
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