High-dose ondansetron reduces activation of interoceptive and sensorimotor brain regions

Several psychiatric disorders involve abnormalities of interoception and associated neural circuitry centered on the insula. The development of interventions modulating interoceptive circuits could lead to novel treatment approaches for these disorders. The 5-HT3 receptor antagonist ondansetron is a...

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Udgivet i:Neuropsychopharmacology
Main Authors: Stern, Emily R., Shahab, Rebbia, Grimaldi, Stephanie J., Leibu, Evan, Murrough, James W., Fleysher, Lazar, Parides, Michael K., Coffey, Barbara J., Burdick, Katherine E., Goodman, Wayne K.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300545/
https://ncbi.nlm.nih.gov/pubmed/30116006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0174-x
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