Structure-Function Relationship of XCL1 Used for in vivo Targeting of Antigen Into XCR1(+) Dendritic Cells

XCL1 is the ligand for XCR1, a chemokine receptor uniquely expressed on cross-presenting dendritic cells (DC) in mouse and man. We are interested in establishing therapeutic vaccines based on XCL1-mediated targeting of peptides or proteins into these DC. Therefore, we have functionally analyzed vari...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Kroczek, Arthur L., Hartung, Evelyn, Gurka, Stephanie, Becker, Martina, Reeg, Nele, Mages, Hans W., Voigt, Sebastian, Freund, Christian, Kroczek, Richard A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300513/
https://ncbi.nlm.nih.gov/pubmed/30619244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02806
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