Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

INTRODUCTION AND OBJECTIVE: Currently, carbon nanostructures are vastly explored materials with potential for future employment in biomedicine. The possibility of employment of diamond nanoparticles (DN), graphene oxide (GO) or graphite nanoparticles (GN) for in vivo applications raises a question o...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Strojny, Barbara, Sawosz, Ewa, Grodzik, Marta, Jaworski, Sławomir, Szczepaniak, Jarosław, Sosnowska, Malwina, Wierzbicki, Mateusz, Kutwin, Marta, Orlińska, Sylwia, Chwalibog, André
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300366/
https://ncbi.nlm.nih.gov/pubmed/30587978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S188997
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