NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice

Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus. However, the stimulatory action of NKB is dependent on circulating estrogen (E(2)) levels, without whic...

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Bibliographic Details
Published in:eLife
Main Authors: Fergani, Chrysanthi, Leon, Silvia, Padilla, Stephanie L, Verstegen, Anne MJ, Palmiter, Richard D, Navarro, Victor M
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300354/
https://ncbi.nlm.nih.gov/pubmed/30565563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40476
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